MidwestSports.Net ranks the top 10 football teams in the midwest region in NCAA Division II and NAIA for Sept. 30, 2018.
DIVISION II
| Ranking | Team | Record | Previous | Last Week / This Week |
| 1 | Southern Arkansas | (5-0) | 1 | Def. Oklahoma Baptist, 55-45 Oct. 6 vs. Southern Nazarene |
| 2 | Pittsburg State | (5-0) | 2 | Def. Lindenwood, 27-24 Oct. 6 vs. Northwest Missouri |
| 3 | Ouachita | (5-0) | 3 | Def. Arkansas Tech, 24-7 Oct. 6 at Harding |
| 4 | Northwest Missouri | (4-1) | 4 | Def. Emporia State, 41-0 Oct. 6 at Pittsburg State |
| 5 | Fort Hays State | (4-1) | 5 | Def. Central Oklahoma, 15-0 Oct. 6 at Emporia State |
| 6 | Harding | (4-1) | 6 | Def. Arkansas-Monticello, 47-21 Oct. 6 vs. Ouachita |
| 7 | Chadron State | (4-1) | 7 | Def. Western State Oct. 6 at Adams State |
| 8 | Missouri S&T | (4-1) | 8 | Def. Southwest Baptist, 48-23 Oct. 6 vs. Indianapolis |
| 9 | Central Missouri | (3-2) | 10 | Def. Missouri Southern, 61-7 Oct. 6 at Central Oklahoma |
| 10 | Missouri Western | (3-2) | NR | Def. Washburn, 38-7 Oct. 6 at Missouri Southern |
NAIA
| Ranking | Team | Record | Previous | Last Week / This Week |
| 1 | Morningside | (5-0) | 1 | Def. Hastings, 65-0 Oct. 6 at Midland |
| 2 | Northwestern (Iowa) | (5-0) | 2 | Def. Doane, 28-25 Oct. 6 vs. Dordt |
| 3 | Evangel | (6-0) | 3 | Def. William Penn, 28-14 Oct. 6 at Graceland |
| 4 | Kansas Wesleyan | (5-0) | 4 | Def. Bethany, 70-24 Oct. 6 vs. St. Mary |
| 5 | Langston | (3-1) | 6 | Def. Wayland Baptist, 31-20 Oct. 6 at Texas Wesleyan |
| 6 | Midland | (4-1) | 7 | Def. Jamestown, 35-28 OT Oct. 6 vs. Morningside |
| 7 | Benedictine | (4-1) | 8 | Def. Baker, 23-12 Oct. 6 vs. Central Methodist |
| 8 | St. Ambrose | (4-1) | NR | Def. St. Francis (Ind), Oct. 6 vs. Marian |
| 9 | Avila | (4-1) | 5 | Lost to Southwestern, 51-49 Oct. 6 Idle |
| 10 | Grand View | (3-1) | 9 | Def. Missouri Valley, 20-13 Oct. 6 vs. MidAmerica Nazarene |